Research on learning has proposed various models for learning. However, generally, there has been an inadequate research of the application of these models for learning for example the Kolb’s experiential learning cycle or the Jarvis’s model of reflection and learning to the development of e-learning materials. This is more so especially due to lack of effective yet practical design model for designing interactive e-learning materials. Having this in mind, the TSOI Hybrid Learning Model can be used as a pedagogic model for the cognitive design of e-learning. This Model represents learning as a cyclical cognitive process. A major feature is to promote active cognitive processing in the learner for meaningful learning proceeding from inductive to deductive. Design specificity in science and chemistry education is illustrated in terms of instructional storyboarding and the research-based e-learning product developed. Learners’ cognitive abilities will be addressed as part of the research data collected.

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