Development of Surgical Tools and Procedures for Experimental Preclinical Surgery Using Computer Simulations And 3D Printing

Jan Barcik; Manuela Ernst; Ronald Schwyn; Linda Freitag; Constantin Edmond Dlaska; Ludmil Drenchev; Stoil Todorov; Hristo Skulev; Devakara R. Epari; Stephan Zeiter; Boyko Gueorguiev

doi:10.3991/ijoe.v16i09.15183

Authors

Jan Barcik 1. AO Research Institute Davos, Clavadelerstrasse 8, 7270 Davos, Switzerland 2. Bulgarian Academy of Sciences, Institute of Metal Science 'Acad. A. Balevski', 67 “Shipchenski prohod”, Sofia 1574, Bulgaria
Manuela Ernst AO Research Institute Davos, Clavadelerstrasse 8, 7270 Davos, Switzerland
Ronald Schwyn AO Research Institute Davos, Clavadelerstrasse 8, 7270 Davos, Switzerland
Linda Freitag AO Research Institute Davos, Clavadelerstrasse 8, 7270 Davos, Switzerland
Constantin Edmond Dlaska Orthopaedic Research Institute of Queensland, 7 Turner Street, Townsville, Queensland, 4812, Australia
Ludmil Drenchev Bulgarian Academy of Sciences, Institute of Metal Science 'Acad. A. Balevski', 67 “Shipchenski prohod”, Sofia 1574, Bulgaria
Stoil Todorov Bulgarian Academy of Sciences, Institute of Metal Science 'Acad. A. Balevski', 67 “Shipchenski prohod”, Sofia 1574, Bulgaria
Hristo Skulev Bulgarian Academy of Sciences, Institute of Metal Science 'Acad. A. Balevski', 67 “Shipchenski prohod”, Sofia 1574, Bulgaria
Devakara R. Epari Queensland University of Technology, Institute of Health and Biomedical Innovation, 2 George St, Brisbane City QLD 4000, Australia
Stephan Zeiter AO Research Institute Davos, Clavadelerstrasse 8,7270 Davos, Switzerland
Boyko Gueorguiev AO Research Institute Davos, Clavadelerstrasse 8,7270 Davos, Switzerland

DOI:

https://doi.org/10.3991/ijoe.v16i09.15183

Keywords:

3D printing, rapid prototyping, experimental surgery, virtual surgery, bone fractures

Abstract

Abstract—Experimental preclinical surgeries require high accuracy and repeatability in all applied procedures. For in vivo studies investigating bone fracture healing it is crucial to create precisely and consistently the experimental bone fractures in all included subjects. In large animal models the required precision is usually achieved by application of dedicated drilling jigs and cutting guides that often need to be individually designed in order to fulfil the requirements of a particular experiment. Moreover, their final design may considerably differ from the prototypes. Hence, the designing and testing processes require multiple iterative refinement loops substantially increasing the costs of the experiment. Therefore, a framework for development of tailor-made instruments for experimental preclinical surgeries is established to reduce the investment of time and financial effort.

Author Biographies

Jan Barcik, 1. AO Research Institute Davos, Clavadelerstrasse 8, 7270 Davos, Switzerland 2. Bulgarian Academy of Sciences, Institute of Metal Science 'Acad. A. Balevski', 67 “Shipchenski prohod”, Sofia 1574, Bulgaria

PhD student Biomedical Development

Manuela Ernst, AO Research Institute Davos, Clavadelerstrasse 8, 7270 Davos, Switzerland

Project Leader Biomedical Development

Ronald Schwyn, AO Research Institute Davos, Clavadelerstrasse 8, 7270 Davos, Switzerland

Project Leader Biomedical Development

Linda Freitag, AO Research Institute Davos, Clavadelerstrasse 8, 7270 Davos, Switzerland

Dr med vet

Constantin Edmond Dlaska, Orthopaedic Research Institute of Queensland, 7 Turner Street, Townsville, Queensland, 4812, Australia

Dr. med. univ. FEBOT FaOrtho

Ludmil Drenchev, Bulgarian Academy of Sciences, Institute of Metal Science 'Acad. A. Balevski', 67 “Shipchenski prohod”, Sofia 1574, Bulgaria

Professor, PhD, D.Sc, Director of the Institute of Metal Science 'Acad. A. Balevski', Bulgarian Academy of Sciences

Stoil Todorov, Bulgarian Academy of Sciences, Institute of Metal Science 'Acad. A. Balevski', 67 “Shipchenski prohod”, Sofia 1574, Bulgaria

Professor, PhD, Head of the Department of Mechanical Devices, Equipment and Technologies, Institute of Metal Science 'Acad. A. Balevski', Bulgarian Academy of Sciences

Hristo Skulev, Bulgarian Academy of Sciences, Institute of Metal Science 'Acad. A. Balevski', 67 “Shipchenski prohod”, Sofia 1574, Bulgaria

Professor, PhD

Devakara R. Epari, Queensland University of Technology, Institute of Health and Biomedical Innovation, 2 George St, Brisbane City QLD 4000, Australia

Associate Professor

Stephan Zeiter, AO Research Institute Davos, Clavadelerstrasse 8,7270 Davos, Switzerland

Program Leader Preclinical Services, Focus Area Leader Preclinical Surgery, PhD, Dr med vet, Dipl ECLAM

Boyko Gueorguiev, AO Research Institute Davos, Clavadelerstrasse 8,7270 Davos, Switzerland

Leader Biomedical Development Program, PhD, Prof