A Systematic Literature Review on Machine Learning in Healthcare Prediction

Authors

  • Nur Farah Afifah Ahmad Sukri Universiti Sultan Zainal Abidin, Terengganu, Malaysia https://orcid.org/0009-0009-7746-7075
  • Wan Mohd Amir Fazamin Wan Hamzah Universiti Sultan Zainal Abidin, Terengganu, Malaysia https://orcid.org/0000-0001-5262-2766
  • Mohd Kamir Yusof Universiti Sultan Zainal Abidin, Terengganu, Malaysia
  • Ismahafezi Ismail Universiti Sultan Zainal Abidin, Terengganu, Malaysia
  • Harmy Mohamed Yusoff Universiti Sultan Zainal Abidin, Terengganu, Malaysia
  • Azliza Yacob Terengganu Advanced Technical Institute, Terengganu, Malaysia

DOI:

https://doi.org/10.3991/ijoe.v21i06.54211

Keywords:

Machine Learning (ML), Machine Learning Operations (MLOPs), machine learning algorithms, machine learning models, healthcare, prediction

Abstract


Rapid technological advancement will continue to create new values and transform experiences in many sectors, including healthcare. Several key trends are shaping today’s healthcare system, including the use of machine learning (ML). This systematic literature review (SLR) explores the application of ML in healthcare, particularly in predictive analytics. The SLR also includes a few papers on machine learning operations (MLOps) in healthcare, reflecting limited studies on the topic. This suggests significant potential for further exploration in MLOps. The review compares findings from various studies, many of which agree that ML enhances the scalability and reliability of predictive models. This study aims to assess the most effective ML algorithms and methodologies used in healthcare prediction. It also attempts to identify features influencing the outcomes of ML applications in healthcare predictions. Findings suggest that ML can improve prediction accuracy using the appropriate dataset, optimal feature selection model, and a tailored ML algorithm for specific tasks. The literature highlights challenges, including the need for specialised skills and the complexity of integrating MLOps into existing healthcare systems.

Author Biographies

Nur Farah Afifah Ahmad Sukri, Universiti Sultan Zainal Abidin, Terengganu, Malaysia

Nur Farah Afifah Ahmad Sukri earned her BSc in Computer Science (Software Development) and MSc in Computer Science from Universiti Sultan Zainal Abidin in 2016 and 2019, respectively. She is currently pursuing a PhD in the Department of Information Technology at the Faculty of Informatics and Computing, Universiti Sultan Zainal Abidin in Terengganu, Malaysia. Previously, she worked as a lecturer and laboratory assistant at Universiti Malaysia Terengganu before starting her PhD. Her research interests include Natural Language Processing, Machine Learning, and Deep Learning. (Email: faraafifah@gmail.com).

Wan Mohd Amir Fazamin Wan Hamzah, Universiti Sultan Zainal Abidin, Terengganu, Malaysia

Wan Mohd Amir Fazamin Wan Hamzah received a B.I.T. degree in Software Engineering, M.Sc. and Ph.D. degree in Computer Science from the Universiti Malaysia Terengganu in 2003, 2010 and 2016, respectively. He is currently a Senior Lecturer with the Faculty of Informatics and Computing, Universiti Sultan Zainal Abidin (UniSZA), Terengganu, Malaysia. His research interests include learning analytics, machine learning, gamification, and e-learning. (Email: amirfazamin@unisza.edu.my).

Mohd Kamir Yusof, Universiti Sultan Zainal Abidin, Terengganu, Malaysia

Mohd Kamir Yusof received the Ph.D. degree from Universiti Malaysia Terengganu. He is currently a senior lecturer in the Department of Computer Science, Faculty of Informatics and Computing. Universiti Sultan Zainal Abidin (UniSZA), Terengganu, Malaysia. His research interests include data integration, and mobile and web application development. (Email: mohdkamir@unisza.edu.my).

Ismahafezi Ismail, Universiti Sultan Zainal Abidin, Terengganu, Malaysia

Ismahafezi Ismail is a Senior Lecturer at the Faculty of Informatics and Computing, Universiti Sultan Zainal Abidin (UniSZA), Terengganu, Malaysia. His research focuses on virtual reality, augmented reality, computer games, and animation. (Email: ismahafezi@unisza.edu.my).

Harmy Mohamed Yusoff, Universiti Sultan Zainal Abidin, Terengganu, Malaysia

Harmy Mohamed Yusoff is the Dean of the Faculty of Medicine, UniSZA with extensive experience and expertise in the field of Family Medicine. With an excellent academic background, he obtained his Master of Medicine (Family Medicine) from Universiti Sains Malaysia in 2002. Prior to that, he obtained his Doctor of Medicine (MD) in 1995 and Bachelor of Science in Medicine (BSc) in 1993, both from Universiti Kebangsaan Malaysia.

Azliza Yacob, Terengganu Advanced Technical Institute, Terengganu, Malaysia

Azliza Yacob is a senior lecturer and a researcher at University College TATI (UCTATI). She received her Bachelor of Science (Computer) and Master of Science (Information Technology – Manufacturing) at University Teknologi Malaysia (UTM) in 2003 and 2005. She also has completed her PhD in Computer Science, from University Malaysia Terengganu in 2018. Her research interest includes e-learning, quality control, decision-support system, computer industry and artificial intelligence. (Email: azliza@uctati.edu.my).

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Published

2025-05-15

How to Cite

Ahmad Sukri, N. F. A., Wan Hamzah, W. M. A. F., Yusof, M. K., Ismail, I., Yusoff, H. M., & Yacob, A. (2025). A Systematic Literature Review on Machine Learning in Healthcare Prediction. International Journal of Online and Biomedical Engineering (iJOE), 21(06), pp. 155–177. https://doi.org/10.3991/ijoe.v21i06.54211

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Papers