Metacognition, Stress – Relaxation Balance & Related Hormones


  • Athanasios Drigas N.C.S.R. "Demokritos"
  • Eleni Mitsea N.C.S.R. "Demokritos"



metacognition, mindfulness, stress, sympathetic & parasympathetic nervous sys-tem, hormones, self-awareness, self-regulation, executive functions, triune brain, brain rewiring, metacognitive strategies


This paper examines the interaction between metacognition and stress response. Specifically, the main purpose of this study is to trace the interaction between metacognition, sympathetic-parasympathetic nervous system and the basic stress-related hormones/neurotransmitters.  To achieve this aim, the research seeks to address the following questions: Can metacognition regulate the stress-related hormones and the sympathetic nervous system hyperactivity? How can it contribute to the regulation of uncontrollable stress? What is the role of executive functions? Can metacognition stop the cells and neurons from degeneration and the brain from shrinking?  The evidence support the hypothesis that there is a deep relationship between metacognition, stress-related hormones and autonomic nervous system. Therefore, the above finding paves the way for the design of new stress management strategies, which could implemented in family, in school and in workplace. Uncontrollable stress constitutes the “health epidemic” of our century. Mental and mood disorders, premature ageing, cognitive impairments, learning disabilities are some of the stress-related threats. There is an urgent need to focus on resilience in order to cope with stress and to stay in balance.

Author Biographies

Athanasios Drigas, N.C.S.R. "Demokritos"

Athanasios S. Drigas is a Research Director at N.C.S.R. “Demokritos”, ΙΙΤ - Net Media Lab & Mind- Brain R&D, Agia Paraskevi, 153 10, Athens, Greece (e-mail:

Eleni Mitsea, N.C.S.R. "Demokritos"

Eleni Mitsea is with Institute of Informatics and Telecommunications - Net Media Lab & Mind-Brain R&D, Agia Paraskevi, 153 10, Athens, Greece (e-mail:




How to Cite

Drigas, A., & Mitsea, E. (2021). Metacognition, Stress – Relaxation Balance & Related Hormones. International Journal of Recent Contributions from Engineering, Science & IT (iJES), 9(1), pp. 4–16.